The risk of second tumors after chimeric antigen receptor (CAR) T-cell therapy, especially the risk of T-cell neoplasms related to viral vector integration, is an emerging concern. A total of 724 ...

Acute kidney injury (AKI) is a serious and common complication of cardiac surgery, for which reduced kidney perfusion is a key contributing factor. Intravenous amino acids increase kidney ...

A 32-year-old man presented with a 7-year history of skin nodules and swelling, pain, and morning stiffness in his fingers ...

Indolent CD4+ cytotoxic chimeric antigen receptor (CAR) T-cell lymphoma involving the small intestine was diagnosed in a patient who had previously received ciltacabtagene autoleucel (cilta-cel ...

A 59-year-old veterinarian presented with a 1-year history of a painful rash on his hand. Verrucous plaques with overlying thick yellow-brown crusting were seen on the dorsum of the hand and the ...

A total of 742 patients underwent randomization, with 371 assigned to each group. The analysis of the primary outcome included 722 patients. The median hemoglobin level in the intensive care unit ...

Among critically ill adults undergoing tracheal intubation, hypoxemia increases the risk of cardiac arrest and death. The effect of preoxygenation with noninvasive ventilation, as compared with ...

The last three decades have seen dramatic advances in the use of immunotherapies to treat cancer, primarily in the form of monoclonal antibodies targeting cancer cells directly or recruiting the ...

Genetic variants that cause rare disorders may remain elusive even after expansive testing, such as exome sequencing. The diagnostic yield of genome sequencing, particularly after a negative ...

Until the United States amends its civil rights statutes to guarantee emergency medical care to people in police custody or contact, countless people will die needlessly while pleading for access ...

Among 15 patients with relapsed ALCL after the failure of brentuximab vedotin therapy, the ALK inhibitor brigatinib led to a complete response in 73%, and progression-free survival at 2 years was 73%.

Medical students and faculty at the University of Pittsburgh have been teaching middle-school students from marginalized racial and ethnic groups how to perform bystander CPR.